Usefulness of the in vivo large field of view confocal line scanning ophthalmoscope in murine

Wen Kong; Wanyue Li; Feng Gao; Xingjie Jin; Jinyu Fan; Guohua Shi

doi:10.1117/12.2521107

12 March 2019 Usefulness of the in vivo large field of view confocal line scanning ophthalmoscope in murine

Wen Kong, Wanyue Li, Feng Gao, Xingjie Jin, Jinyu Fan, Guohua Shi

Author Affiliations +

Proceedings Volume 11023, Fifth Symposium on Novel Optoelectronic Detection Technology and Application; 1102349 (2019) https://doi.org/10.1117/12.2521107
Event: Fifth Symposium on Novel Optoelectronic Detection Technology and Application, 2018, Xi'an, China

Abstract

Mouse is one of the most common animal models used in retinal researching, and obtaining its fundus images in vivo have significant significance for finding out formation and development mechanism of retinopathy, resolution and field-of-view are the key in fundus imaging. In this paper, we present an ophthalmoscope based on line scanning confocal technology, which utilizes one-dimension scanning line beam to increase image resolution and frame rate, it could capture mouse fundus at 1730*1730 μm field of view and 24 fps frame rate, retinal capillaries and vessels could be distinguished through reflectance and fluorescent images.

Citation Download Citation

Wen Kong, Wanyue Li, Feng Gao, Xingjie Jin, Jinyu Fan, and Guohua Shi "Usefulness of the in vivo large field of view confocal line scanning ophthalmoscope in murine", Proc. SPIE 11023, Fifth Symposium on Novel Optoelectronic Detection Technology and Application, 1102349 (12 March 2019); https://doi.org/10.1117/12.2521107

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