Evaluation of the relationship between symptomatic assessment, corneal staining and tear meniscus by image analysis

Silvia Garcia-Montero; Dolores Ferreiro; Covadonga Vazquez-Sanchez; Hugo Pena-Verdeal; Eva Yebra-Pimentel

doi:10.1117/12.2527352

3 October 2019 Evaluation of the relationship between symptomatic assessment, corneal staining and tear meniscus by image analysis

Silvia Garcia-Montero, Dolores Ferreiro, Covadonga Vazquez-Sanchez, Hugo Pena-Verdeal, Eva Yebra-Pimentel

Author Affiliations +

Proceedings Volume 11207, Fourth International Conference on Applications of Optics and Photonics; 112071D (2019) https://doi.org/10.1117/12.2527352
Event: IV International Conference on Applications of Optics and Photonics (AOP 2019), 2019, Lisbon, Portugal

Abstract

Purpose: Vital staining is one of the most widely test used to evaluate the corneal damage. The aim of this study was to assess the relationship of the corneal damage with tear meniscus height (TMH) and dry eye symptomatology. Material and methods: 530 subjects were recruited among patients of the Optometry Clinic (USC). Previously, all of them completed an OSDI questionnaire. Two videos of the ocular surface were recorded from each patient by a digital camera attached to a slit-lamp. Firstly, a video of central tear meniscus under 40x with the Tearscope device illumination was recorded. From those videos, a masked observer extracted one image and TMH was measured by using the ImageJ software. Secondly, after fluorescein instillation, the corneal surface was recorded by another experienced masked observer, who assigned a category to the corneal damaged based on the Oxford Scheme. The evaluation was stratified by corneal zones based on the CCLRU grading scales (central, superior, inferior, nasal and temporal). Results: When the sample was grouped by the corneal staining Oxford Grade, there was found a statistical difference between groups in OSDI and TMH value (ANOVA: both p≤0.006). There was found a difference in OSDI value when corneal damage was in nasal or inferior areas (t-test; both p≤0.015), and a difference in TMH value arises when damage was in the central, nasal or inferior areas (t-test; all p≤0.013). Conclusions: There is a relationship between corneal damage grade and corneal zones with dry eye symptomatology and tear film volume.

Citation Download Citation

Silvia Garcia-Montero, Dolores Ferreiro, Covadonga Vazquez-Sanchez, Hugo Pena-Verdeal, and Eva Yebra-Pimentel "Evaluation of the relationship between symptomatic assessment, corneal staining and tear meniscus by image analysis", Proc. SPIE 11207, Fourth International Conference on Applications of Optics and Photonics, 112071D (3 October 2019); https://doi.org/10.1117/12.2527352

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
6 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Eye

Statistical analysis

Image analysis

Video

Digital cameras

Digital video recorders

Inflammation

Show All Keywords

Keywords/Phrases

Search In:

Publication Years