Endoscopic polarization-sensitive OCT using spun fiber (Conference Presentation)

Saijun Qiu; Yan Li; Zhongping Chen

doi:10.1117/12.2545351

6 March 2020 Endoscopic polarization-sensitive OCT using spun fiber (Conference Presentation)

Saijun Qiu, Yan Li, Zhongping Chen

Author Affiliations +

Proceedings Volume 11214, Endoscopic Microscopy XV; 112140S (2020) https://doi.org/10.1117/12.2545351
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) provides cross-sectional images of different polarization states, which can be utilized to obtain additional properties of biological tissue, such as birefringence. It has been demonstrated that collagen secreted by smooth muscle cells (SMC) is highly associated with the stability of atherosclerotic plaques; since both collagen and SMC are birefringent, endoscopic PS-OCT may provide a means to quantitatively analyze the risks and stability of atherosclerotic plaques. Here, we developed a compact spun-fiber-based PS-OCT to achieve robust imaging. In this work, the phase retardation map and OCT images of an ex vivo cadaver coronary artery are presented, and the birefringence of the collagen and SMC is identified.

Conference Presentation

Citation Download Citation

Saijun Qiu, Yan Li, and Zhongping Chen "Endoscopic polarization-sensitive OCT using spun fiber (Conference Presentation)", Proc. SPIE 11214, Endoscopic Microscopy XV, 112140S (6 March 2020); https://doi.org/10.1117/12.2545351

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KEYWORDS

Endoscopy

Optical coherence tomography

Collagen

Polarization

Birefringence

Structured optical fibers

Arteries

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