Olga A. Bibikova,1 Valentin Mironovich,1 Iskander Usenov,1 Elena Feliksberger,1 Alexey Bocharnikov,1 Anastasia Surkova,2 Valeria Belikova,2 Ervin Nippolainen,3 Isaac Afara,3 Julian Haas,4 Vesa Virtanen,5 Lassi Rieppo,5 Harold Brommer,6 René van Weeren,6 Michael Pleyer,7 Johannes Koethhttps://orcid.org/0009-0007-6696-4100,7 Markus Nägele,8 Juha Töyräs,3 Boris Mizaikoff,9 Tatiana Sakharova,1 Viacheslav Artyushenko1
1art photonics GmbH (Germany) 2Samara State Technical Univ. (Russian Federation) 3Univ. of Eastern Finland (Finland) 4Univ. Ulm (Germany) 5Research Unit of Medical Imaging, Physics and Technology, Univ. of Oulu (Finland) 6Utrecht Univ. (Netherlands) 7Nanoplus Nanosystems and Technologies GmbH (Germany) 8OptoPrecision GmbH (Germany) 9Institute of Analytical and Bioanalytical Chemistry, Univ. Ulm (Germany)
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Combination of FTIR spectroscopy with fiber optics provides a powerful diagnostic tool for diagnosing of human diseases, including osteoarthritis. To detect cartilage degradation, an arthroscopic probe based on polycrystalline fibers was developed and evaluated on equine cartilage specimen. The hook shape allows reaching a significant portion of the articular surface; the flat tip ensures avoidance of tissue destruction. Efficient QCL-coupling and stable transmission of PIR fibers under bending allows the assembling of effective thin arthroscopy probes and customized multispectral systems for medical diagnostic applications. The presented work was performed within the MIRACLE project (Grant Agreement No 780598, Horizon 2020).
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Olga A. Bibikova, Valentin Mironovich, Iskander Usenov, Elena Feliksberger, Alexey Bocharnikov, Anastasia Surkova, Valeria Belikova, Ervin Nippolainen, Isaac Afara, Julian Haas, Vesa Virtanen, Lassi Rieppo, Harold Brommer, René van Weeren, Michael Pleyer, Johannes Koeth, Markus Nägele, Juha Töyräs, Boris Mizaikoff, Tatiana Sakharova, Viacheslav Artyushenko, "Mid-infrared fiber spectroscopy for detection of cartilage degeneration in osteoarthritis (Conference Presentation)," Proc. SPIE 11233, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX, 112330J (9 March 2020); https://doi.org/10.1117/12.2544893