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Intrinsic and extrinsic aging of human skin induces significant morphological changes to its surface. The most prominent and important feature in cosmetics and dermatology is the alteration of the wrinkles. Roughness parameters (Ra, Rmax) described by DIN/ISO disregard the skin’s micro-structure. Hence, we introduce an alternative method of skin roughness evaluation by analyzing the size and shape of micro-structures using optical coherence tomography. Measurements of young and elderly subjects were acquired. The skin of elderly subjects showed a decrease in micro-structures compared to the skin of young subjects which was predominated by triangular shapes, whereas rhomboids prevail among the elderly.
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Felix Hilge, Michael Evers, Malte Casper, Joshua Zev Glahn, Weeranut Phothong M.D., Garuna Kositratna M.D., Hinnerk Schulz-Hildebrandt, Gereon Hüttmann, Dieter Manstein M.D., "Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography," Proc. SPIE 11618, Photonics in Dermatology and Plastic Surgery 2021, 116180A (5 March 2021); https://doi.org/10.1117/12.2577822