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5 March 2021 Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging
Inga Saknīte, Shinwho Kwun, Xiaoqi Liu, Kathy Zhang, Alexis Hood, Fuyao Chen, Lauri Kangas, Ari Kukkonen, Pirjo Kortteisto, Michael Byrne, Madan Jagasia, Eric R. Tkaczyk
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Proceedings Volume 11618, Photonics in Dermatology and Plastic Surgery 2021; 116180J (2021) https://doi.org/10.1117/12.2578532
Event: SPIE BiOS, 2021, Online Only
Abstract
Through vertex component analysis of hyperspectral imaging data in the visible spectral range, we differentiated erythematous and pigmented areas in patients with cutaneous chronic graft-versus-host disease. We explored the feasibility of hyperspectral imaging in combination with unsupervised learning algorithms to differentiate active disease from inactive post-inflammatory skin changes, a fundamental practice gap in caring for these patients. We compared erythema and pigment maps to the visual assessment by a dermatologist as the ground truth.
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Inga Saknīte, Shinwho Kwun, Xiaoqi Liu, Kathy Zhang, Alexis Hood, Fuyao Chen, Lauri Kangas, Ari Kukkonen, Pirjo Kortteisto, Michael Byrne, Madan Jagasia, and Eric R. Tkaczyk "Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging", Proc. SPIE 11618, Photonics in Dermatology and Plastic Surgery 2021, 116180J (5 March 2021); https://doi.org/10.1117/12.2578532
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KEYWORDS
Hyperspectral imaging
Skin
Fiber optic illuminators
Halogens
Prototyping
Sensors
Stem cells
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