Aurelian Marcu,1 Razvan Ungureanu,1 Bogdan Calin,1 Raluca Ianchis,2 Sevinci Pop,3 Mihai Serbanescu,1 Gabriel Cojocaru1
1Institutul National pentru Fizica Laserilor, Plasmei si Radiatiei (Romania) 2ICHECHIM (Romania) 3Institutul National de Cercetare-Dezvoltare "Victor Babes" (Romania)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
In-situ fabrication of (magnetic) iron based nanoparticles is demonstrated using ultrashort laser pulses ablation in liquid medium. Using this in-situ method, thermal effects associated with other similar methods are avoided because of pulse duration much beyond 1 ps, avoiding thermal processes as well as chemical contamination and clustering issues during particle fabrication or transfer steps. Size distribution proved to be dependent on laser beam pulse duration and energy, while their surface (zeta-)potential did not. Monitoring of the cellular viability in the presence of the produced nanoparticles showed an excellent bio-compatibility but with rather limited drug loading capabilities in the absence of any surface functionalization.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.