Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd:YAG laser: early clinical results

Christopher J. White M.D.; Stephen R. Ramee M.D.; Juan E. Mesa M.D.; Larry H. Hollier M.D.; Joseph P. Murgo M.D.; Michael Aita; Gene Samson; Maureen A. Godfrey

doi:10.1117/12.17538

1 July 1990 Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd:YAG laser: early clinical results

Christopher J. White M.D., Stephen R. Ramee M.D., Juan E. Mesa M.D., Larry H. Hollier M.D., Joseph P. Murgo M.D., Michael Aita, Gene Samson, Maureen A. Godfrey

Author Affiliations +

Proceedings Volume 1201, Optical Fibers in Medicine V; (1990) https://doi.org/10.1117/12.17538
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

We performed a clinical trial to evaluate the safety and efficacy of a unique lensed-fiber delivery system with a pulsed Neodymium-yttrium aluminum garnet (Nd-YAG) laser in patients with atherosclerotic peripheral vascular disease. The lensed-fiber consists of a spherical silica lens, 1 .5 mm in diameter, mounted at the distal tip of a 300 im silica optical fiber. The Nd-YAG laser is pulsed at 10 Hz, and we delivered 0.5 J/pulse with a pulse duration of 100 msecs in 2- to 5-second bursts. Successful recanalization of stenoses or occlusions was obtained in 9 of 10 patients and was manifested by improvement in blood flow as measured angiographically and with ankle-brachial blood pressure index improvement (> 0. 15). There were no arterial perforations or dissections associated with the laser angioplasty. All successfully recanalized patients required adjunctive balloon angioplasty to obtain a satisfactory reduction in luminal diameter stenosis of the treated artery. We conclude that this unique delivery system and the pulsed Nd-YAG laser are a safe and effect method of recanalizing arterial stenoses not amenable to conventional balloon angioplasty alone.

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Christopher J. White M.D., Stephen R. Ramee M.D., Juan E. Mesa M.D., Larry H. Hollier M.D., Joseph P. Murgo M.D., Michael Aita, Gene Samson, and Maureen A. Godfrey "Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd:YAG laser: early clinical results", Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); https://doi.org/10.1117/12.17538

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