Blood glucose analysis by Raman spectrophotometer with ellipsoidal reflector

Andrii Haponiuk; Natalia Bezugla; Kostiantyn Vonsevych; Mikhail Bezuglyi; Aliya Zilgaraeva; Piotr Kisala; Saule Luganskaya; Sandugash Orazalieva

doi:10.1117/12.2613340

3 November 2021 Blood glucose analysis by Raman spectrophotometer with ellipsoidal reflector

Andrii Haponiuk, Natalia Bezugla, Kostiantyn Vonsevych, Mikhail Bezuglyi, Aliya Zilgaraeva, Piotr Kisala, Saule Luganskaya, Sandugash Orazalieva

Author Affiliations +

Proceedings Volume 12040, Photonics Applications in Astronomy, Communications, Industry, and High Energy Physics Experiments 2021; 120400B (2021) https://doi.org/10.1117/12.2613340
Event: Photonics Applications in Astronomy, Communications, Industry, and High Energy Physics Experiments 2021 (WILGA 2021), 2021, Warsaw, Poland

Abstract

Authors considered the possibility of designing a non-invasive biomedical Raman spectrophotometer for the near infrared range using an ellipsoidal reflector as a collecting and focusing optical element to evaluation the biological media components, particularly glucose level. The technical solution for creating the spectrophotometer and its prototype are presented in this paper. The research of the experimental setup was observed faster and more sensitive photodetector reaction to the dynamic blood glucose changes of concentration. Practical testing was carried out by the Raman shift signal measuring on healthy volunteers at different time intervals with food intake associated. The experimental setup principles can be used to design a portable non-invasive glucometer or to quantitatively analyses the chemical composition of biological objects by changing Raman filters.

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Andrii Haponiuk, Natalia Bezugla, Kostiantyn Vonsevych, Mikhail Bezuglyi, Aliya Zilgaraeva, Piotr Kisala, Saule Luganskaya, and Sandugash Orazalieva "Blood glucose analysis by Raman spectrophotometer with ellipsoidal reflector", Proc. SPIE 12040, Photonics Applications in Astronomy, Communications, Industry, and High Energy Physics Experiments 2021, 120400B (3 November 2021); https://doi.org/10.1117/12.2613340

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KEYWORDS

Raman spectroscopy

Reflectors

Spectrophotometry

Glucose

Optical filters

Blood

Photodiodes

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