On the 18th January 2003 the devastating Canberra firestorm completely destroyed all of the Mount Stromlo telescopes, technology development workshops, much of the observatory infrastructure. The Advanced Instrumentation Technology Centre (AITC) was established (2006) in the aftermath as a world-class facility to support the development of the next generation of instruments for astronomy and space science. In this paper describe the integrated portfolio, project, quality and system engineering management processes, that have been implemented in order to operate the AITC as a primarily financially self-supporting, University based, instrumentation centre within the highly volatile and rapidly evolving business landscape of today, i.e. what has helped the AITC to survive, and even thrive, during the highly turbulent years, also what has been developed, evolved, strengthen and even eliminated from our structure and operational practices.
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