Interpolated template subtraction method for stimulation artifact removal

Chui Kong; Yingnan Nie; Shouyan Wang

doi:10.1117/12.2651410

15 March 2023 Interpolated template subtraction method for stimulation artifact removal

Chui Kong, Yingnan Nie, Shouyan Wang

Proceedings Volume 12438, AI and Optical Data Sciences IV; 1243817 (2023) https://doi.org/10.1117/12.2651410
Event: SPIE OPTO, 2023, San Francisco, California, United States

Conference Poster

Abstract

Recording of the local field potentials(LFPs) and calcium signal is strongly influenced by external stimuli. However, stimulation artifacts are difficult to isolate from the signal. Current studies generally screen out trial segments with high stimulus amplitude. To keep more information of the traces, We propose a method to remove the negative effects of deep brain stimulation (DBS) on LFPs, this method performs well in dealing with periodic artifacts with high amplitude, large pulse width and high stimulation frequency, which may also alleviate artifacts of neuronal calcium signaling trajectories introduced during imaging.

Citation Download Citation

Chui Kong, Yingnan Nie, and Shouyan Wang "Interpolated template subtraction method for stimulation artifact removal", Proc. SPIE 12438, AI and Optical Data Sciences IV, 1243817 (15 March 2023); https://doi.org/10.1117/12.2651410

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