Thyroid cancer is the most common type of neoplasm in the head and neck regions, thermal imaging has been used successfully for medical diagnostic purposes in areas such as breast cancer, wound care, vascular diseases, skin cancer and eye diseases. The thyroid is a richly vascularized gland that is located close to the skin, its hyper or hypo activity modifies the temperature pattern of the neck making thermography a good candidate to evaluate possible pathologies by digital infrared thermography. In this work an Artificial Neural Network based on the Nested U-Net architecture is trained and used to detect thyroid pathologies. Two thermographic databases were used to train the artificial neural network, the dataset was split into 80% for training and 20% for testing, with cross-validation used to evaluate the network's performance. The error between the predicted masks and the actual masks is calculated with the combination of Binary Cross Entropy (BCE) Loss and Dice Loss using Adam algorithm as training rule, with a cosine annealing schedule during 1500 epochs with a learning rate of 0.003 and a batch size of 6. Results show that when calculating the correlation coefficient between these deltas and the results of thyroid ultrasound expressed in the ACR TI-RADS classification, a high degree of correlation is obtained.
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