Comparison of algorithms for the estimation of the optical attenuation coefficients in optical coherence tomography

Nian Peng; Xiaoyu Yang; Chengli Xu; Kerui Li; Haixia Qiu; Ying Gu; Defu Chen

doi:10.1117/12.2688870

29 November 2023 Comparison of algorithms for the estimation of the optical attenuation coefficients in optical coherence tomography

Nian Peng, Xiaoyu Yang, Chengli Xu, Kerui Li, Haixia Qiu, Ying Gu, Defu Chen

Author Affiliations +

Proceedings Volume 12770, Optics in Health Care and Biomedical Optics XIII; 1277038 (2023) https://doi.org/10.1117/12.2688870
Event: SPIE/COS Photonics Asia, 2023, Beijing, China

Conference Poster

Abstract

Various algorithms have been proposed to compute attenuation coefficient (AC) based on optical coherence tomography (OCT) signals. The single scattering model has gained widespread application due to its computational efficiency; however, it’s only applicable to thin tissue layers, thus imposing strict requirements on the data length used for calculations. This study compared the algorithms for estimating the AC from OCT data using different data length such as 180 μm , 250 μm , 350 μm , 435 μm acquired from intralipid phantoms. Subsequently, employing various algorithms and utilizing the optimal data length, we calculated the attenuation coefficients of liquid phantoms with different concentrations, and the methodology was applied to homogeneous mouse tissues. The comparative study may provide a reliable basis for parameter configuration for AC extraction algorithm.

Citation Download Citation

Nian Peng, Xiaoyu Yang, Chengli Xu, Kerui Li, Haixia Qiu, Ying Gu, and Defu Chen "Comparison of algorithms for the estimation of the optical attenuation coefficients in optical coherence tomography", Proc. SPIE 12770, Optics in Health Care and Biomedical Optics XIII, 1277038 (29 November 2023); https://doi.org/10.1117/12.2688870

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