Efficient 4D reconstruction of the beating embryonic heart with a single, linearly scanned, densely sampled 3D OCT image

Andre C. Faubert; Shang Wang

doi:10.1117/12.3008576

13 March 2024 Efficient 4D reconstruction of the beating embryonic heart with a single, linearly scanned, densely sampled 3D OCT image

Andre C. Faubert, Shang Wang

Author Affiliations +

Proceedings Volume 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024; 128190N (2024) https://doi.org/10.1117/12.3008576
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Cardiodynamics and hemodynamics are important factors regulating heart development, but dynamic 3D imaging of a beating embryonic heart has been challenging due to high requirements for both imaging scale and speed. Optical coherence tomography (OCT) has a unique imaging scale for 3D embryonic heart imaging in various animal models. However, the general imaging speed of OCT can only provide limited spatiotemporal sampling in direct volumetric acquisition of a beating heart. Here, we present an open-source, post-acquisition synchronization method that requires just a single, densely sampled linear 3D scan but generates superior 4D (3D+time) imaging quality with a high efficiency.

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Andre C. Faubert and Shang Wang "Efficient 4D reconstruction of the beating embryonic heart with a single, linearly scanned, densely sampled 3D OCT image", Proc. SPIE 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024, 128190N (13 March 2024); https://doi.org/10.1117/12.3008576

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KEYWORDS

Heart

Optical coherence tomography

3D image reconstruction

3D image processing

3D scanning

Medical image reconstruction

3D acquisition

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