Repeated acute hypotension induced by thigh cuff release and cerebral oxygenation changes

Atsuhiro Tsubaki; Hajime Tamiya; Hiroki Baba; Taiki Miyajima; Shinichiro Morishita

doi:10.1117/12.3003451

12 March 2024 Repeated acute hypotension induced by thigh cuff release and cerebral oxygenation changes

Atsuhiro Tsubaki, Hajime Tamiya, Hiroki Baba, Taiki Miyajima, Shinichiro Morishita

Proceedings Volume 12838, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables V; 1283806 (2024) https://doi.org/10.1117/12.3003451
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Normal brain function depends on stable cerebral blood flow and autoregulation. Cerebral blood flow is maintained even when blood pressure fluctuates in daily life. However, microcirculation in the cortex, when blood pressure drops rapidly and repeatedly, is poorly understood. This study aimed to determine oxyhemoglobin (O₂Hb) levels, which may reflect cortical blood flow changes, during repeated hypotension cycles induced by thigh cuff release. Twelve healthy students participated in this study. Each participant was seated in the recumbent position in a quiet room. Cuffs of digital tourniquets were placed on both thighs and inflated to 250 mmHg for 5 min after 5 min of rest, followed by deflation for 5 min, which was repeated four times. Right (R) and left (L) prefrontal cortex (PFC) O₂Hb levels were measured using a multichannel near-infrared spectroscopy system (LABNIRS; Shimadzu Co., Tokyo, Japan). Beat-to-beat mean arterial pressure (MAP) was recorded by finger pulse volume using photoplethysmography (Finometer; Finapres Medical Systems, Amsterdam, the Netherlands), and O₂Hb and MAP were averaged over 1-s epochs throughout the study. Ultimately, there were no significant changes in MAP or O₂Hb levels among the four measurements. This study demonstrates that repeated hypotension induced by thigh cuff release does not lead to any lowering effects on MAP or O₂Hb.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Atsuhiro Tsubaki, Hajime Tamiya, Hiroki Baba, Taiki Miyajima, and Shinichiro Morishita "Repeated acute hypotension induced by thigh cuff release and cerebral oxygenation changes", Proc. SPIE 12838, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables V, 1283806 (12 March 2024); https://doi.org/10.1117/12.3003451

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