Metal carbonyl loaded nanoparticles for breast cancer biomarker detection

Craig Richard; Pei-Hsuan Hsieh; Matthew Confer; Rohit Bhargava

doi:10.1117/12.3002618

13 March 2024 Metal carbonyl loaded nanoparticles for breast cancer biomarker detection

Craig Richard, Pei-Hsuan Hsieh, Matthew Confer, Rohit Bhargava

Proceedings Volume 12858, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI; 1285805 (2024) https://doi.org/10.1117/12.3002618
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

The potential advantages of infrared spectroscopic imaging for examination of cells and tissue biopsies for cancer histopathology is high, however there are fundamental limitations of FTIR that must first be addressed. One limitation is that Infrared spectroscopy lacks the sensitivity to detect biomarkers of disease directly. With cancer being one of the leading causes of death and its increasing prevalence, it is important to develop tools that can rapidly screen and enable rapid and simultaneous fingerprinting of biologic content and metabolic state. To address these limitations, probed Infrared spectroscopy is being explored. We report the successful synthesis, characterization, and application of metal carbonyl loaded nanoparticle probes for the detection of breast cancer biomarkers.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Craig Richard, Pei-Hsuan Hsieh, Matthew Confer, and Rohit Bhargava "Metal carbonyl loaded nanoparticles for breast cancer biomarker detection", Proc. SPIE 12858, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI, 1285805 (13 March 2024); https://doi.org/10.1117/12.3002618

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