Maria Y. Berezovskaya,1 Pavel V. Filatov,1 Polina S. Luganskaja,1 Alexandra V. Afanasjeva,1 Daria A. Gorbenko,1 Maria D. Rubel,1 Daler R. Dadadzhanov,1 Tigran A. Vartanyan1
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Detection of nucleic acids has become a promising approach in diagnostics, but current methods often have limitations such as the need for expensive equipment or reduced sensitivity and specificity. Tuberculosis caused by M. tuberculosis is a widespread infectious disease that is also prone to developing antibiotic resistance. In this study, we introduce a novel method for detection and genotyping of M. tuberculosis using a biosensor based on a four-way junction (4WJ) DNA probe and plasmon Au nanospheres.
(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
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Maria Y. Berezovskaya, Pavel V. Filatov, Polina S. Luganskaja, Alexandra V. Afanasjeva, Daria A. Gorbenko, Maria D. Rubel, Daler R. Dadadzhanov, Tigran A. Vartanyan, "Conjugates of DNA and plasmonic nanoparticles for the development of an SPR sensor for nucleic acids," Proc. SPIE 13008, Biophotonics in Point-of-Care III, 130080U (20 June 2024); https://doi.org/10.1117/12.3022750