Paper
18 June 2024 Preliminary evaluation of an automated autoencoder-UNet pipeline for chemical image segmentation and compression with reference to serial ground truth pathology
Author Affiliations +
Abstract
The rapid advancement of imaging technologies in pathology has ushered in an era of data-intensive diagnostic workflows, generating large volumes of data that demand sophisticated segmentation and compression techniques. Chemical imaging approaches offer an all-digital objective approach to pathological analysis, though image segmentation is required for efficient computation.

Convolutional autoencoders are highly connected deep learning networks which can learn salient features within imaging data for the purposes of compression, data recovery, development of classifiers and/or segmentation.

In this study an objective analysis of a U-Net convolutional autoencoders for unsupervised image segmentation is conducted with respect to haematoxylin-eosin based ground-truth diagnostic pathology. We find that a light-weight network architecture may provide a suitable segmentation approach for chemical imaging.
(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
Mohd Rifqi Rafsanjani, Thomas O'Brien, Karin Jirstrom, Arman Rahman, Jochen H. M. Prehn, William Gallagher, and Aidan D. Meade "Preliminary evaluation of an automated autoencoder-UNet pipeline for chemical image segmentation and compression with reference to serial ground truth pathology", Proc. SPIE 13011, Data Science for Photonics and Biophotonics, 130110D (18 June 2024); https://doi.org/10.1117/12.3022279
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KEYWORDS
Image segmentation

Image compression

Imaging spectroscopy

FT-IR spectroscopy

Pathology

Tissues

Data modeling

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