Dynamic vs static bending rigidities for DNA and M13 virus

J. Michael Schurr; Lu Song; Ug-Sung Kim

doi:10.1117/12.57321

1 May 1991 Dynamic vs static bending rigidities for DNA and M13 virus

J. Michael Schurr, Lu Song, Ug-Sung Kim

Proceedings Volume 1403, Laser Applications in Life Sciences; (1991) https://doi.org/10.1117/12.57321
Event: Laser Applications in Life Sciences, 1990, Moscow, Russian Federation

Abstract

A recently developed theory for weakly bending rods provides a means to estimate the dynamic bending rigidities of filamentous macromolecules from transient electro-optic and dynamic light scattering experiments. This theory is applied to analyze transient electric dichroisrn data from Prschke''s laboratory and transient electric birefringence data from Eden''s laboratory for DNA restriction fragments with 95 to 250 bp and also to analyze dynamic light scattering data for M13 virus. Surprisingly the dynamic bending rigidity of DNA is about three times the consensus static value inferred from its equilibrium persistence length. This implies that the bending potential of DNA is non-simple and/or biased. In contrast the dynamic and static bending rigidities of M13 virus are nearly identical so its bending potential is simple and unbiased. 1.

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J. Michael Schurr, Lu Song, and Ug-Sung Kim "Dynamic vs static bending rigidities for DNA and M13 virus", Proc. SPIE 1403, Laser Applications in Life Sciences, (1 May 1991); https://doi.org/10.1117/12.57321

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