Pharmaceutical process development and optimization using in-situ Fourier transform infrared spectroscopy

Alan J. Rein

doi:10.1117/12.137757

14 August 1992 Pharmaceutical process development and optimization using in-situ Fourier transform infrared spectroscopy

Alan J. Rein

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Proceedings Volume 1681, Optically Based Methods for Process Analysis; (1992) https://doi.org/10.1117/12.137757
Event: SPIE's 1992 Symposium on Process Control and Monitoring, 1992, Somerset, NJ, United States

Abstract

Fourier transform infrared spectroscopy (FTIR) is being applied successfully in process development and optimization of bulk chemicals in the pharmaceutical industry. The speed and specificity of FTIR affords great advantages in the study of these chemical processes. Reactants, intermediates, and products can be monitored in-situ and in real time, under reaction conditions.

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Alan J. Rein "Pharmaceutical process development and optimization using in-situ Fourier transform infrared spectroscopy", Proc. SPIE 1681, Optically Based Methods for Process Analysis, (14 August 1992); https://doi.org/10.1117/12.137757

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