1.5-um resolution optical low-coherence reflectometry in biological tissues

Xavier Clivaz; Fabienne D. Marquis-Weible; Rene-Paul Salathe

doi:10.1117/12.167408

1 February 1994 1.5-μm resolution optical low-coherence reflectometry in biological tissues

Xavier Clivaz, Fabienne D. Marquis-Weible, Rene-Paul Salathe

Author Affiliations +

Proceedings Volume 2083, Microscopy, Holography, and Interferometry in Biomedicine; (1994) https://doi.org/10.1117/12.167408
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

An Optical Low Coherence Reflectometer with a spatial resolution of 1.5 micrometers (FWHM) in biological tissue has been developed. This high resolution is obtained using the fluorescence generated by an Ar-laser pumped Ti-Sapphire crystal. Measurements have been performed on freshly excised pig eyes and bovine mesenteric arterial walls, as examples of transparent and diffusive biological tissues, respectively. The improved spatial resolution is used to determine more precisely optical distances and to resolve details of the intima structure.

Citation Download Citation

Xavier Clivaz, Fabienne D. Marquis-Weible, and Rene-Paul Salathe "1.5-μm resolution optical low-coherence reflectometry in biological tissues", Proc. SPIE 2083, Microscopy, Holography, and Interferometry in Biomedicine, (1 February 1994); https://doi.org/10.1117/12.167408

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