Effect of tin etiopurpurin and light on the canine prostate

Steven H. Selman M.D.; Rick W. Keck; Daniel R. Doiron

doi:10.1117/12.203365

1 March 1995 Effect of tin etiopurpurin and light on the canine prostate

Steven H. Selman M.D., Rick W. Keck, Daniel R. Doiron

Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203365
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States

Abstract

A series of experiments was undertaken to determine the effects of the combination of light and the tissue photosensitizer, tin etiopurpurin, on the canine prostate. Mongrel dogs were injected intravenously with 1.0 mg/kg of photosensitizer twenty-four hours prior to light delivery. Laser light, 660 nm, was administered either transurethrally or interstitially and tissue effects were assessed by histopathologic examination. Both techniques of light delivery resulted in hemorrhagic necrosis of the surrounding tissue. Photodynamic therapy may offer a novel approach to the treatment of both benign and malignant diseases of the prostate.

Citation Download Citation

Steven H. Selman M.D., Rick W. Keck, and Daniel R. Doiron "Effect of tin etiopurpurin and light on the canine prostate", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); https://doi.org/10.1117/12.203365

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