Measurements of the edge spread function on a realistic tissue phantom

Antonio Pifferi; Rinaldo Cubeddu; Paola Taroni; Alessandro Torricelli; Gianluca Valentini

doi:10.1117/12.280277

18 August 1997 Measurements of the edge spread function on a realistic tissue phantom

Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni, Alessandro Torricelli, Gianluca Valentini

Proceedings Volume 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II; (1997) https://doi.org/10.1117/12.280277
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

A simple and reliable solid tissue phantom, made of agar, intralipid and ink is described and characterized. Following a standardized preparation procedure, it is fast and easy to produce inhomogeneous structures with known optical properties and a high degree of repeatability. The proposed phantom is used to measure the edge-profile produced by abrupt variations of either the 'absorption or the scattering coefficient in a turbid slab. The samples were scanned using a system for time- resolved transmittance measurements, based on a mode-locked dye laser and an electronic chain for time-correlated single- photon counting. The photon time-distributions were then interpreted either with a solution of the diffusion equation or with a time-gating. The plots of the transport scattering coefficient, of the absorption coefficient, and of the intensity integrated over an early time-interval as a function of position can give insight into the problem of spatial resolution and the mechanism of imaging through diffusive media with different techniques.

Citation Download Citation

Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni, Alessandro Torricelli, and Gianluca Valentini "Measurements of the edge spread function on a realistic tissue phantom", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280277

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