OCT monitoring of pathophysiological processes

Natalia D. Gladkova; Natalia M. Shakhova; Andrei Shakhov; Galina P. Petrova; Elena Zagainova; Ludmila Snopova; Irina N. Kuznetzova; Yuri Chumakov; Felix I. Feldchtein; Valentin M. Gelikonov; Grigory V. Gelikonov; Vladislav A. Kamensky; Roman V. Kuranov; Alexander M. Sergeev

doi:10.1117/12.347477

30 April 1999 OCT monitoring of pathophysiological processes

Natalia D. Gladkova, Natalia M. Shakhova, Andrei Shakhov, Galina P. Petrova, Elena Zagainova, Ludmila Snopova, Irina N. Kuznetzova, Yuri Chumakov, Felix I. Feldchtein, Valentin M. Gelikonov, Grigory V. Gelikonov, Vladislav A. Kamensky, Roman V. Kuranov, Alexander M. Sergeev

Author Affiliations +

Proceedings Volume 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III; (1999) https://doi.org/10.1117/12.347477
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Based on results of clinical examination of about 200 patients we discuss capabilities of the optical coherence tomography (OCT) in monitoring and diagnosing of various pathophysiological processes. Performed in several clinical areas including dermatology, urology, laryngology, gynecology, and dentistry, our study shows the existence of common optical features in manifestation of a pathophysiological process in different organs. In this paper we focus at such universal tomographic optical signs for processes of inflammation, necrosis and tumor growth. We also present data on dynamical OCT monitoring of evolution of pathophysiological processes, both at the stage of disease development and following-up results of different treatments such as drug application, radiation therapy, cryodestruction, and laser vaporization. The discovered peculiarities of OCT images for structural and functional imaging of biological tissues can be put as a basis for application of this method for diagnosing of pathology, guidance of treatment, estimation of its adequacy and assessing of the healing process.

Citation Download Citation

Natalia D. Gladkova, Natalia M. Shakhova, Andrei Shakhov, Galina P. Petrova, Elena Zagainova, Ludmila Snopova, Irina N. Kuznetzova, Yuri Chumakov, Felix I. Feldchtein, Valentin M. Gelikonov, Grigory V. Gelikonov, Vladislav A. Kamensky, Roman V. Kuranov, and Alexander M. Sergeev "OCT monitoring of pathophysiological processes", Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); https://doi.org/10.1117/12.347477

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available