Fluorescence spectrum of normal and carcinoma human lung tissue

Changqing Yu; Yan Zhang; Haihua Song; Yi He; Jixiang Yan; Jiaze Li

doi:10.1117/12.403992

11 October 2000 Fluorescence spectrum of normal and carcinoma human lung tissue

Changqing Yu, Yan Zhang, Haihua Song, Yi He, Jixiang Yan, Jiaze Li

Proceedings Volume 4224, Biomedical Photonics and Optoelectronic Imaging; (2000) https://doi.org/10.1117/12.403992
Event: Optics and Optoelectronic Inspection and Control: Techniques, Applications, and Instruments, 2000, Beijing, China

Abstract

Laser-induced fluorescence (LIF) is a promising method for pre-malignant lung tissue diagnosis and it is very important to find effective common diagnosis criteria needed by clinic. In this paper, some differences between normal and cancer lung tissue, such as I₄₄₄/I₄₁₄ ratio, main peak width, and integral area were exhibited and discussed. By using the fourth harmonic at 266nm of a Q-switched Nd:YAG laser as an excitation source, Optical Multi-channel Analyzer (OMA) as a detector, laser-induced fluorescence spectra of normal and cancer lung tissue in-vitro were measured. According to the spectra characteristics, three independent diagnosis criteria were obtained and analyzed. The total specificity is above 95%.

Citation Download Citation

Changqing Yu, Yan Zhang, Haihua Song, Yi He, Jixiang Yan, and Jiaze Li "Fluorescence spectrum of normal and carcinoma human lung tissue", Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); https://doi.org/10.1117/12.403992

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available