Photoacoustic imaging of a biological sample using in-phase-sum focus algorithm

Wanshao Cai; Zhilei Tang; Da Xing

doi:10.1117/12.403983

11 October 2000 Photoacoustic imaging of a biological sample using in-phase-sum focus algorithm

Wanshao Cai, Zhilei Tang, Da Xing

Proceedings Volume 4224, Biomedical Photonics and Optoelectronic Imaging; (2000) https://doi.org/10.1117/12.403983
Event: Optics and Optoelectronic Inspection and Control: Techniques, Applications, and Instruments, 2000, Beijing, China

Abstract

Photoacoustic (PA) imaging is a new imaging modality, which converts pressure signals received by an array of transducers to a regional distribution of electromagnetic absorption density. In this paper we present an experiment result of a photoacoustic imaging to depths of approximately 3mm for a fabricated absorber within a real tissue, using a 1064-nm pulse YAG laser. The time-resolved stress detection technique was used for PA signal detection and an in-phase- sum-focus algorithm was used for image reconstruction. To obtain excellent temporal resolution, a wideband PVDF membrane hydrophone and a fast-digitizing oscilloscope was used for time-resolved detection of PA signals. A computer controlled translation stage on which the sample cell was fixed was used to a 2D scanning mode. Images of different depth profile was obtained with a lateral and depth resolution of approximately 0.5mm.

Citation Download Citation

Wanshao Cai, Zhilei Tang, and Da Xing "Photoacoustic imaging of a biological sample using in-phase-sum focus algorithm", Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); https://doi.org/10.1117/12.403983

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KEYWORDS

Signal detection

Tissues

Acoustics

Photoacoustic imaging

Tissue optics

Transducers

Pulsed laser operation

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