Experimental data for in vitro and in vivo studies of various solutions action on optical properties of human tissues is presented. The dynamics of tissue optical properties depending on matter diffusion rate within tissue is studied. The possible application of refractive index matching effect for tissue imaging is discussed. Results on optical properties control of the human sclera, skin, connective tissue membranes, such as dura mater, muscle and blood due to their impregnation by the osmotically active chemicals, such as trazograph, glucose, propylene glycol, glycerol are presented.
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