Paper
12 September 2002 New advancement of noninvasive measurement of blood glucose by near-infrared spectroscopy
Qingbo Li, Yan Wang, Kexin Xu
Author Affiliations +
Abstract
Noninvasive blood glucose measurement with near-infrared spectroscopy suitable for home use would allow a more accuracy and frequent determination of glucose level, along with reducing the long-term health care costs of diabetic patients due to no reagents. The fundamental research results of noninvasive blood glucose sensing of our research group are introduced in this paper. They are involving the aspects as followed, the prediction results of the fundamental experiments by PLS calibration method and artificial neural networks respectively; the wavelength selection by genetic algorithm; the quantitative relation among prediction accuracy, instrumental precision and regression algorithms; and the determination of measuring mode according to the measuring wavelength range, and so on. The experiments that done with the samples from simple ones to complex ones have proved the feasibility of noninvasive blood glucose measurement methodology by near-infrared spectroscopy. In addition, the further research subjects of the fundamental problems involving human body measurement are proposed.
© (2002) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Qingbo Li, Yan Wang, and Kexin Xu "New advancement of noninvasive measurement of blood glucose by near-infrared spectroscopy", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.483007
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KEYWORDS
Glucose

Blood

Calibration

Absorption

Near infrared spectroscopy

Signal to noise ratio

Genetic algorithms

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