Perfusion weighted imaging and its application in stroke

Enzhong Li M.D.; Jie Tian; Ying Han; Huifang Wang; Xingfeng Li; Fuping Zhu

doi:10.1117/12.480279

2 May 2003 Perfusion weighted imaging and its application in stroke

Enzhong Li M.D., Jie Tian, Ying Han, Huifang Wang, Xingfeng Li, Fuping Zhu

Proceedings Volume 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications; (2003) https://doi.org/10.1117/12.480279
Event: Medical Imaging 2003, 2003, San Diego, California, United States

Abstract

To study the technique and application of perfusion weighted imaging (PWI) in the diagnosis and medical treatment of acute stroke, 25 patients were examined by 1.5 T or 1.0 T MRI scanner. The Data analysis was done with "3D Med System" developed by our Lab to process the data and obtain apparent diffusion coefficient (ADC) map, cerebral blood volume (CBV) map, cerebral blood flow (CBF) map as well as mean transit time (MTT) map. In accute stage of stroke, normal or slightly hypointensity in T1-, hyperintensity in T2- and diffusion-weighted images were seen in the cerebral infarction areas. There were hypointensity in CBV map, CBF map and ADC map; and hyperintensity in MTT map that means this infarct area could be saved. If the hyperintensity area in MTT map was larger than the area in diffusion weighted imaging (DWI), the larger part was called penumbra and could be cured by an appropriate thrombolyitic or other therapy. The CBV, CBF and MTT maps are very important in the diagnosis and medical treatment of acute especially hyperacute stroke. Comparing with DWI, we can easily know the situation of penumbra and the effect of curvative therapy. Besides, we can also make a differential diagnosis with this method.

Citation Download Citation

Enzhong Li M.D., Jie Tian, Ying Han, Huifang Wang, Xingfeng Li, and Fuping Zhu "Perfusion weighted imaging and its application in stroke", Proc. SPIE 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, (2 May 2003); https://doi.org/10.1117/12.480279

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