Study delay and dispersion effects in dynamic susceptibility contrast MRI based on local density random walk distribution

Xingfeng Li; Jie Tian; Xiaoxiang Wang; Jianping Dai; Lin Ai

doi:10.1117/12.536185

30 April 2004 Study delay and dispersion effects in dynamic susceptibility contrast MRI based on local density random walk distribution

Xingfeng Li, Jie Tian, Xiaoxiang Wang, Jianping Dai, Lin Ai

Author Affiliations +

Proceedings Volume 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images; (2004) https://doi.org/10.1117/12.536185
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

The aim of this study was to assess the validation of the local density random walk (LDRW) function to correct the delayed and dispersed arterial input function (AIF) data derived from dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI). Instead of using the gamma-variate function to smooth and extrapolate the AIF curves, we suggested a method which was based on diffusion with drift approach. Forty-seven AIF curves from ten patients were segmented to test the effectiveness of the proposed method. The results of the comparisons with the gamma-variate function showed that the LDRW distribution function may provide a new means for more accurate correction of AIF curves.

Citation Download Citation

Xingfeng Li, Jie Tian, Xiaoxiang Wang, Jianping Dai, and Lin Ai "Study delay and dispersion effects in dynamic susceptibility contrast MRI based on local density random walk distribution", Proc. SPIE 5369, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, (30 April 2004); https://doi.org/10.1117/12.536185

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