Automated slide-screening platform for histo/pathology

Rainer Daum; Andreas Achtermann; Rainer Uhl

doi:10.1117/12.729554

18 July 2007 Automated slide-screening platform for histo/pathology

Rainer Daum, Andreas Achtermann, Rainer Uhl

Proceedings Volume 6631, Novel Optical Instrumentation for Biomedical Applications III; 66311D (2007) https://doi.org/10.1117/12.729554
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

We have developed a novel platform-concept, which allows the construction of an automated upright light-microscope-based slide-scanning device. In order to achieve maximal speed at maximal image quality we have paid special attention to a highly rigid, highly stiff construction. By using novel materials we have been able to achieve vibration-damping characteristics many times better than conventional approaches. We have combined these new concepts with a voice-coil based digitally controlled focus drive, which achieves the speed and stability of a piezo-element, yet allows travels of up to 10 mm. Using scan-modes which avoid stop & go but instead keep the slide moving at a constant speed we have been able to cut scan-times to levels approaching that of multi-objective approaches, yet with much higher flexibility and better image quality.

Citation Download Citation

Rainer Daum, Andreas Achtermann, and Rainer Uhl "Automated slide-screening platform for histo/pathology", Proc. SPIE 6631, Novel Optical Instrumentation for Biomedical Applications III, 66311D (18 July 2007); https://doi.org/10.1117/12.729554

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