Combined swept-source optical coherence tomography and fluorescence spectroscopy system

Seon Young Ryu; Myeong Jin Ju; Kwan Seob Park; Joo Beom Eom; Byeong Ha Lee

doi:10.1117/12.841478

23 February 2010 Combined swept-source optical coherence tomography and fluorescence spectroscopy system

Seon Young Ryu, Myeong Jin Ju, Kwan Seob Park, Joo Beom Eom, Byeong Ha Lee

Proceedings Volume 7557, Multimodal Biomedical Imaging V; 75570W (2010) https://doi.org/10.1117/12.841478
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We report a combined swept source optical coherence tomography (SSOCT) and fluorescence spectroscopy (FS) system for multimodal measurements of biochemical information and internal structures with fast imaging speed. The FS probe composed of a double clad fiber (DCF) coupler is adopted into the single mode fiber based SSOCT system. Here, the DCF coupler acts as a FS system as well as a multifunctional probe for the SSOCT-FS system. The performances of the single-unit SSOCT-FS system is confirmed by monitoring the fluorescence signal from photosensitizer in cancerous region of in-vivo rat and by imaging the internal structures of same region with speed of 40 frames/sec.

Citation Download Citation

Seon Young Ryu, Myeong Jin Ju, Kwan Seob Park, Joo Beom Eom, and Byeong Ha Lee "Combined swept-source optical coherence tomography and fluorescence spectroscopy system", Proc. SPIE 7557, Multimodal Biomedical Imaging V, 75570W (23 February 2010); https://doi.org/10.1117/12.841478

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