Simple method of improving sensitivity for diffuse reflective optical tomography: simulation and a phantom study

Keiko Fukuda; Kazuaki Koishi; Takanobu Murayama

doi:10.1117/12.889352

14 June 2011 Simple method of improving sensitivity for diffuse reflective optical tomography: simulation and a phantom study

Keiko Fukuda, Kazuaki Koishi, Takanobu Murayama

Author Affiliations +

Proceedings Volume 8088, Diffuse Optical Imaging III; 80881C (2011) https://doi.org/10.1117/12.889352
Event: European Conferences on Biomedical Optics, 2011, Munich, Germany

Abstract

A new method for cancelling the skin blood flow in functional near-infrared spectroscopy (fNIRS) is proposed to improve the measurement accuracy of oxygen consumption in a brain tissue. We proposed to use two kinds of cancellation signals. One is a sharing aperture approach which uses cancellation signals detected at apertures for irradiating the light. Another one is an additional aperture approach which uses cancellation signals detected at the midpoint between the irradiation and detection aperture in conventional measurement. We further applied an equilateral-triangular probe arrangement to our method. For the equilateral-triangular probe arrangement, the cancellation signal of the sharing aperture approach is detected at apex, and the cancellation signal of the additional aperture approach is detected at the median point of the equilateral-triangular. Simulation and experiments with a phantom were performed. Simulation results show that the proposed method effectively detected the influence of the near-surface absorption change, which depends on its position and size, by automatically selecting the two kinds of cancellation signal.

Citation Download Citation

Keiko Fukuda, Kazuaki Koishi, and Takanobu Murayama "Simple method of improving sensitivity for diffuse reflective optical tomography: simulation and a phantom study", Proc. SPIE 8088, Diffuse Optical Imaging III, 80881C (14 June 2011); https://doi.org/10.1117/12.889352

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KEYWORDS

Signal detection

Absorption

Tissue optics

Sensors

Blood circulation

Brain

Oxygen

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