Mechanical compression for contrasting OCT images of biotissues

Mikhail Yu Kirillin; Pavel D. Argba; Vladislav A. Kamensky

doi:10.1117/12.889844

1 June 2011 Mechanical compression for contrasting OCT images of biotissues

Mikhail Yu Kirillin, Pavel D. Argba, Vladislav A. Kamensky

Proceedings Volume 8091, Optical Coherence Tomography and Coherence Techniques V; 80910N (2011) https://doi.org/10.1117/12.889844
Event: European Conferences on Biomedical Optics, 2011, Munich, Germany

Abstract

Contrasting of biotissue layers in OCT images after application of mechanical compression is discussed. The study is performed on ex vivo samples of human rectum, and in vivo on skin of human volunteers. We show that mechanical compression provides contrasting of biotissue layer boundaries due to different mechanical properties of layers. We show that alteration of pressure from 0 up to 0.45 N/mm² causes contrast increase from 1 to 10 dB in OCT imaging of human rectum ex vivo. Results of ex vivo studies are in good agreement with Monte Carlo simulations. Application of pressure of 0.45 N/mm² causes increase in contrast of epidermis-dermis junction in OCT-images of human skin in vivo for about 10 dB.

Citation Download Citation

Mikhail Yu Kirillin, Pavel D. Argba, and Vladislav A. Kamensky "Mechanical compression for contrasting OCT images of biotissues", Proc. SPIE 8091, Optical Coherence Tomography and Coherence Techniques V, 80910N (1 June 2011); https://doi.org/10.1117/12.889844

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available