Optoacoustic temperature monitoring during HIFU impact on biological tissues: ex vivo study and numerical simulations of 2D temperature reconstruction

Sergey Nikitin; Tatiana Khokhlova; Ivan Pelivanov

doi:10.1117/12.909079

28 February 2012 Optoacoustic temperature monitoring during HIFU impact on biological tissues: ex vivo study and numerical simulations of 2D temperature reconstruction

Sergey Nikitin, Tatiana Khokhlova, Ivan Pelivanov

Author Affiliations +

Proceedings Volume 8223, Photons Plus Ultrasound: Imaging and Sensing 2012; 822313 (2012) https://doi.org/10.1117/12.909079
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Dependencies of the optoacoustic (OA) transformation efficiency on tissue temperature were obtained for the application in OA temperature monitoring during thermal therapies. Accurate measurement of the OA signal amplitude versus temperature was performed in different ex-vivo tissues in the temperature range 25°C - 80°C. The investigated tissues were selected to represent different structural components: chicken breast (skeletal muscle), porcine lard (fatty tissue) and porcine liver (richly perfused tissue). Backward mode of the OA signal detection and a narrow probe laser beam were used in the experiments to avoid the influence of changes in light scattering with tissue coagulation on the OA signal amplitude. Measurements were performed in heating and cooling regimes. Characteristic behavior of the OA signal amplitude temperature dependences in different temperature ranges were described in terms of changes in different structural components of the tissue samples. Finally, numerical simulation of the OA temperature monitoring with a linear transducers array was performed to demonstrate the possibility of real-time temperature mapping.

Citation Download Citation

Sergey Nikitin, Tatiana Khokhlova, and Ivan Pelivanov "Optoacoustic temperature monitoring during HIFU impact on biological tissues: ex vivo study and numerical simulations of 2D temperature reconstruction", Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 822313 (28 February 2012); https://doi.org/10.1117/12.909079

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
14 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tissues

Temperature metrology

Liver

Signal detection

Transducers

Absorption

Breast

Show All Keywords

Keywords/Phrases

Search In:

Publication Years