Synthesis and characterization of NIR light-responsive LbL nanocapsules

Xue-mei Chi; Jie Cao; Shu-nan Wan; Chang-li Du; Wei R. Chen; Yue-qing Gu

doi:10.1117/12.907783

14 February 2012 Synthesis and characterization of NIR light-responsive LbL nanocapsules

Xue-mei Chi, Jie Cao, Shu-nan Wan, Chang-li Du, Wei R. Chen, Yue-qing Gu

Proceedings Volume 8224, Biophotonics and Immune Responses VII; 82240J (2012) https://doi.org/10.1117/12.907783
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

In this paper, near-infrared (NIR) light responsive polyelectrolyte multilayer capsules (PE/Au NRs@Dox) were successfully synthesized by layer-by-layer techniques. Gold nanorods with aspect ratio of 3.9, and a longitudinal absorbance peak at 765nm were prepared using seed-mediated method which used the cationic surfactant cetyltrimethylammonium bromide (CTAB) as a soft template and structure-guiding agent. Sequential layers of polyanions (sodium polystyrene sulfonate (PSS)) and polycations (poly diallyldimethylammonium chloride (PDADMAC)) were followed by adsorption of three BSA/PSS bilayers. The doxorubicin (Dox) is loaded by the electrostatic interaction. The release of Dox from the swelling polyelectrolyte complex PE/Au NRs@Dox was induced by the heat generated from gold nanorods under laser irradiation. Moreover, the in vitro cytotoxicity of PE/Au NRs@Dox and the doxorubicin release from the composites were investigated.

Citation Download Citation

Xue-mei Chi, Jie Cao, Shu-nan Wan, Chang-li Du, Wei R. Chen, and Yue-qing Gu "Synthesis and characterization of NIR light-responsive LbL nanocapsules", Proc. SPIE 8224, Biophotonics and Immune Responses VII, 82240J (14 February 2012); https://doi.org/10.1117/12.907783

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available