Optic disk localization by a robust fusion method

Jielin Zhang; Fengshou Yin; Damon W. K. Wong; Jiang Liu; Mani Baskaran; Ching-Yu Cheng; Tien Yin Wong

doi:10.1117/12.2006339

28 February 2013 Optic disk localization by a robust fusion method

Jielin Zhang, Fengshou Yin, Damon W. K. Wong, Jiang Liu, Mani Baskaran, Ching-Yu Cheng, Tien Yin Wong

Author Affiliations +

Proceedings Volume 8670, Medical Imaging 2013: Computer-Aided Diagnosis; 86702G (2013) https://doi.org/10.1117/12.2006339
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

The optic disk localization plays an important role in developing computer-aided diagnosis (CAD) systems for ocular diseases such as glaucoma, diabetic retinopathy and age-related macula degeneration. In this paper, we propose an intelligent fusion of methods for the localization of the optic disk in retinal fundus images. Three different approaches are developed to detect the location of the optic disk separately. The first method is the maximum vessel crossing method, which finds the region with the most number of blood vessel crossing points. The second one is the multichannel thresholding method, targeting the area with the highest intensity. The final method searches the vertical and horizontal region-of-interest separately on the basis of blood vessel structure and neighborhood entropy profile. Finally, these three methods are combined using an intelligent fusion method to improve the overall accuracy. The proposed algorithm was tested on the STARE database and the ORIGA^light database, each consisting of images with various pathologies. The preliminary result on the STARE database can achieve 81.5%, while a higher result of 99% can be obtained for the ORIGA^light database. The proposed method outperforms each individual approach and state-of-the-art method which utilizes an intensity-based approach. The result demonstrates a high potential for this method to be used in retinal CAD systems.

Citation Download Citation

Jielin Zhang, Fengshou Yin, Damon W. K. Wong, Jiang Liu, Mani Baskaran, Ching-Yu Cheng, and Tien Yin Wong "Optic disk localization by a robust fusion method", Proc. SPIE 8670, Medical Imaging 2013: Computer-Aided Diagnosis, 86702G (28 February 2013); https://doi.org/10.1117/12.2006339

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KEYWORDS

Databases

Blood vessels

Optical discs

Image fusion

Pathology

Computer aided diagnosis and therapy

Macula

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