Effect of stretching DNA on lac Repressor 1D-diffusion revealed by the combination of single-molecule localization and manipulation

G. Belcastro; C. Mónico; M. Capitanio; F. Vanzi; F. S. Pavone

doi:10.1117/12.2032514

17 June 2013 Effect of stretching DNA on lac Repressor 1D-diffusion revealed by the combination of single-molecule localization and manipulation

G. Belcastro, C. Mónico, M. Capitanio, F. Vanzi, F. S. Pavone

Author Affiliations +

Proceedings Volume 8797, Advanced Microscopy Techniques III; 87970M (2013) https://doi.org/10.1117/12.2032514
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Here we report the effect of DNA tension on lac repressor 1D-diffusion through a combination of single-molecule localization and optical trapping. The diffusion coefficient shows a parabolic dependence on DNA tension.

Citation Download Citation

G. Belcastro, C. Mónico, M. Capitanio, F. Vanzi, and F. S. Pavone "Effect of stretching DNA on lac Repressor 1D-diffusion revealed by the combination of single-molecule localization and manipulation", Proc. SPIE 8797, Advanced Microscopy Techniques III, 87970M (17 June 2013); https://doi.org/10.1117/12.2032514

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