Estimation of weighted multi-scatterer contributions for improvement of lateral resolution of optical coherence tomography images

Evgenia Bousi; Costas Pitris

doi:10.1117/12.2032671

18 June 2013 Estimation of weighted multi-scatterer contributions for improvement of lateral resolution of optical coherence tomography images

Evgenia Bousi, Costas Pitris

Author Affiliations +

Proceedings Volume 8802, Optical Coherence Tomography and Coherence Techniques VI; 88020D (2013) https://doi.org/10.1117/12.2032671
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

A method for improvement of lateral resolution in Optical Coherence Tomography (OCT) is presented. The resolution improvement achieved with this method does not depend on the delivery optics. Moreover the depth of focus is not restricted. The method is based on the lateral oversampling of the image. The laterally oversampled signals are backscattered signals from shifted and overlapped resolution volumes. Signals from successive volumes are correlated due to the region shared by adjacent resolution volumes. By utilizing the cross correlation of signals from such overlapped volumes, resolution can be improved by various degrees depending on which pairs of signals are used. To maximize the resolution improvement for a given oversampling factor, signals from the farthest spaced and overlapped resolution volumes should be processed. The cost of the resolution refinement is the increasing statistical error because the magnitude of the cross-correlation function becomes smaller. In this method signals from all overlapped volumes are combined optimally to improve the resolution using all the available cross correlations. Preliminary results of such an approach on laterally oversampled OCT images have shown that it is possible to achieve a 3.7-fold lateral resolution improvement.

Citation Download Citation

Evgenia Bousi and Costas Pitris "Estimation of weighted multi-scatterer contributions for improvement of lateral resolution of optical coherence tomography images", Proc. SPIE 8802, Optical Coherence Tomography and Coherence Techniques VI, 88020D (18 June 2013); https://doi.org/10.1117/12.2032671

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available