Development of a robust and fast calibration procedure for diffuse optical tomography

Chen Xu; Hai Li; Guangqian Yuan; Hamed Vavadi; Quing Zhu

doi:10.1117/12.2084980

12 March 2015 Development of a robust and fast calibration procedure for diffuse optical tomography

Chen Xu, Hai Li, Guangqian Yuan, Hamed Vavadi, Quing Zhu

Author Affiliations +

Proceedings Volume 9319, Optical Tomography and Spectroscopy of Tissue XI; 93192E (2015) https://doi.org/10.1117/12.2084980
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Near infrared (NIR) diffuse optical tomography has demonstrated great potential in the initial diagnosis of tumor and the assessment of tumor vasculature response to neoadjuvant chemotherapy. A fast and robust data processing is critical to move this technique from lab research to bench-side application. Our lab developed frequency-domain diffuse optical tomography system for clinical applications. So far, we still collect data at hospital and do the data processing off-line. In this paper, a robust calibration procedure and fast processing program were developed to overcome this limitation. Because each detection channel had its own electronic delay, the calibration procedure measured amplitude linearity and phase linearity of each channel, and formed a look-up table. The experimental measurements were corrected by the table and the fitting accuracy improved by 45.8%. To further improve the processing speed, the data collection and processing program were converted to C++ from matlab program. The overall processing speed was improved by two times. We expect the new processing program can move diffuse optical tomography one step close to bench-side clinical applications.

Citation Download Citation

Chen Xu, Hai Li, Guangqian Yuan, Hamed Vavadi, and Quing Zhu "Development of a robust and fast calibration procedure for diffuse optical tomography", Proc. SPIE 9319, Optical Tomography and Spectroscopy of Tissue XI, 93192E (12 March 2015); https://doi.org/10.1117/12.2084980

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Calibration

Data processing

Diffuse optical tomography

Ultrasonography

Sensors

Near infrared

Breast

Show All Keywords

Keywords/Phrases

Search In:

Publication Years