Optical characterization of pancreatic normal and tumor tissues with double integrating sphere system

Tugba Kiris; Saadet Akbulut; Aysenur Kiris; Zuhal Gucin; Oguzhan Karatepe; Gamze Bölükbasi Ates; Haşim Özgür Tabakoğlu

doi:10.1117/12.2082732

5 March 2015 Optical characterization of pancreatic normal and tumor tissues with double integrating sphere system

Tugba Kiris, Saadet Akbulut, Aysenur Kiris, Zuhal Gucin, Oguzhan Karatepe, Gamze Bölükbasi Ates, Haşim Özgür Tabakoğlu

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Proceedings Volume 9321, Optical Interactions with Tissue and Cells XXVI; 932116 (2015) https://doi.org/10.1117/12.2082732
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

In order to develop minimally invasive, fast and precise diagnostic and therapeutic methods in medicine by using optical methods, first step is to examine how the light propagates, scatters and transmitted through medium. So as to find out appropriate wavelengths, it is required to correctly determine the optical properties of tissues. The aim of this study is to measure the optical properties of both cancerous and normal ex-vivo pancreatic tissues. Results will be compared to detect how cancerous and normal tissues respond to different wavelengths. Double-integrating-sphere system and computational technique inverse adding doubling method (IAD) were used in the study. Absorption and reduced scattering coefficients of normal and cancerous pancreatic tissues have been measured within the range of 500-650 nm. Statistical significant differences between cancerous and normal tissues have been obtained at 550 nm and 630 nm for absorption coefficients. On the other hand; there were no statistical difference found for scattering coefficients at any wavelength.

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Tugba Kiris, Saadet Akbulut, Aysenur Kiris, Zuhal Gucin, Oguzhan Karatepe, Gamze Bölükbasi Ates, and Haşim Özgür Tabakoğlu "Optical characterization of pancreatic normal and tumor tissues with double integrating sphere system", Proc. SPIE 9321, Optical Interactions with Tissue and Cells XXVI, 932116 (5 March 2015); https://doi.org/10.1117/12.2082732

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