Volumetric imaging of fast biological dynamics in deep tissue via wavefront engineering

Lingjie Kong; Jianyong Tang; Meng Cui

doi:10.1117/12.2211417

15 March 2016 Volumetric imaging of fast biological dynamics in deep tissue via wavefront engineering

Lingjie Kong, Jianyong Tang, Meng Cui

Proceedings Volume 9717, Adaptive Optics and Wavefront Control for Biological Systems II; 97170J (2016) https://doi.org/10.1117/12.2211417
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

To reveal fast biological dynamics in deep tissue, we combine two wavefront engineering methods that were developed in our laboratory, namely optical phase-locked ultrasound lens (OPLUL) based volumetric imaging and iterative multiphoton adaptive compensation technique (IMPACT). OPLUL is used to generate oscillating defocusing wavefront for fast axial scanning, and IMPACT is used to compensate the wavefront distortions for deep tissue imaging. We show its promising applications in neuroscience and immunology.

Citation Download Citation

Lingjie Kong, Jianyong Tang, and Meng Cui "Volumetric imaging of fast biological dynamics in deep tissue via wavefront engineering", Proc. SPIE 9717, Adaptive Optics and Wavefront Control for Biological Systems II, 97170J (15 March 2016); https://doi.org/10.1117/12.2211417

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