Quantitative analysis of hair follicles using a serial optical coherence microscopy(OCM)

Eun Ji Lee; Sangjin Lee; Myung-Ju Kim; Yujin Ahn; Woonggyu Jung

doi:10.1117/12.2650959

17 March 2023 Quantitative analysis of hair follicles using a serial optical coherence microscopy(OCM)

Eun Ji Lee, Sangjin Lee, Myung-Ju Kim, Yujin Ahn, Woonggyu Jung

Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520R (2023) https://doi.org/10.1117/12.2650959
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Monitoring hair follicle development is important to interpret hair pathophysiology and follicular-related diseases such as alopecia, folliculitis, acne, and keratosis pilaris. We introduce label-free visualization of hair follicles based on optical coherence microscopy (OCM) and quantitative analysis of the structure using OCM imaging data. The hair follicle regeneration of mice was monitored using our home-built serial OCM. Through this process, we obtained the volumetric anatomy and functional feature of the hair follicle. We also quantified the hair follicle structure including hair root, bulb, papilla, and follicle wall based on OCM data. Our result provides insight into the hair cycle investigation.

Conference Presentation

Citation Download Citation

Eun Ji Lee, Sangjin Lee, Myung-Ju Kim, Yujin Ahn, and Woonggyu Jung "Quantitative analysis of hair follicles using a serial optical coherence microscopy(OCM)", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520R (17 March 2023); https://doi.org/10.1117/12.2650959

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