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17 March 2023 Detection of seminiferous tubules harboring spermatozoa by optical coherence tomography in a rat model of non-obstructive azoospermia
Luyang Yu, Yan He Lue, Hang Yang, Junze Liu, Carlos Vega, Kevin Ho, Christina Wang, Ron Swerdloff, B. Hyle Park
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Proceedings Volume PC12353, Advanced Photonics in Urology 2023; PC1235302 (2023) https://doi.org/10.1117/12.2650746
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Microsurgical testicular sperm extraction (micro-TESE) is a surgical procedure that extracts sperm directly from testicular tissue for patients suffering from non-obstructive azoospermia (NOA). A more accurate and non-invasive visualization method is needed for assisting surgeons to increase the success rate and decrease the damage to patients. In this study, we developed a customized spectrum domain optical coherence tomography(SD-OCT) system for visualization of sperm within seminiferous tubules in NOA rat model. Our results show a 92.78% for detection of pockets of sperm, demonstrating the potential for the use of OCT for improved guidance in micro-TESE.
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Luyang Yu, Yan He Lue, Hang Yang, Junze Liu, Carlos Vega, Kevin Ho, Christina Wang, Ron Swerdloff, and B. Hyle Park "Detection of seminiferous tubules harboring spermatozoa by optical coherence tomography in a rat model of non-obstructive azoospermia", Proc. SPIE PC12353, Advanced Photonics in Urology 2023, PC1235302 (17 March 2023); https://doi.org/10.1117/12.2650746
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KEYWORDS
Optical coherence tomography
Microscopes
Visualization
Data processing
Signal attenuation
Surgery
Testis
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