In-vivo multimodal single-shot off-axis FF-OCT (SO-FF-OCT) imaging:  optical tomography and shear wave elastography

Emmanuel Martins Seromenho; Agathe Marmin; Sybille Facca; Nadia Bahlouli; Amir Nahas

doi:10.1117/12.2652601

9 March 2023 In-vivo multimodal single-shot off-axis FF-OCT (SO-FF-OCT) imaging: optical tomography and shear wave elastography

Emmanuel Martins Seromenho, Agathe Marmin, Sybille Facca, Nadia Bahlouli, Amir Nahas

Author Affiliations +

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC1236718 (2023) https://doi.org/10.1117/12.2652601
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Full-field optical coherence tomography (FF-OCT) enables high-resolution 3D imaging. FF-OCT is a noninvasive and label-free imaging technique that produces high-resolution microscopy images of scattering biological samples. During the last decade, FF-OCT has become invaluable for many biomedical applications. It requires the extraction of the amplitude and phase components from the interference signal, for which a phase-shifting algorithm is usually used. However, this algorithm is not well adapted for real-time observation of in-vivo samples, therefore limiting the use of FF-OCT for ¬in-vivo imaging and clinical transfer. We propose in this study a new approach in FF-OCT that enables single-shot acquisitions using off-axis digital holography principle with low spatially and temporally coherent source.

Conference Presentation

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Emmanuel Martins Seromenho, Agathe Marmin, Sybille Facca, Nadia Bahlouli, and Amir Nahas "In-vivo multimodal single-shot off-axis FF-OCT (SO-FF-OCT) imaging: optical tomography and shear wave elastography", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC1236718 (9 March 2023); https://doi.org/10.1117/12.2652601

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KEYWORDS

Elastography

In vivo imaging

Optical imaging

Optical tomography

Biomedical optics

Optical coherence tomography

Phase shifts

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