Imaging and depth classification of skin microvasculature for skin cancer detection with dynamic laser speckle contrast imaging (DLSCI)

Giulia Mansutti; Martin Villiger; Brett E Bouma; Néstor Uribe-Patarroyo

doi:10.1117/12.3002932

13 March 2024 Imaging and depth classification of skin microvasculature for skin cancer detection with dynamic laser speckle contrast imaging (DLSCI)

Giulia Mansutti, Martin Villiger, Brett E Bouma, Néstor Uribe-Patarroyo

Author Affiliations +

Proceedings Volume PC12816, Photonics in Dermatology and Plastic Surgery 2024; PC128160P (2024) https://doi.org/10.1117/12.3002932
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We present the first laser speckle imaging device for skin cancer detection that can image and distinguish shallow and deep vessels from speckle frames acquired with a single exposure time. To do this, we have developed a new signal processing technique based on the simultaneous evaluation of two metrics: one based on contrast, and one based on a normalized version of the second order autocorrelation function, to reveal deep and shallow vessels, respectively. We will present data from the pilot studies we are conducting on healthy volunteers and skin cancer patients at MGH skin cancer clinic, in which we will compare the microvasculature images obtained with our device from different skin lesions.

Conference Presentation

Citation Download Citation

Giulia Mansutti, Martin Villiger, Brett E Bouma, and Néstor Uribe-Patarroyo "Imaging and depth classification of skin microvasculature for skin cancer detection with dynamic laser speckle contrast imaging (DLSCI)", Proc. SPIE PC12816, Photonics in Dermatology and Plastic Surgery 2024, PC128160P (13 March 2024); https://doi.org/10.1117/12.3002932

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