Evaluating biomechanical properties is crucial to manage skin care and help guide skin cosmetic and reconstruction procedures. Wave-based OCE tracks mechanical waves propagating along the skin surface, where wave speed is used to reconstruct skin elasticity. The first obstacle to quantifying skin elasticity is anisotropy, i.e. 3 shear moduli must be determined. Second, the surface wave group velocity, usually measured experimentally, is very different from the phase velocity needed for elasticity reconstruction. Here we propose methods to overcome these challenges, test the methods using numerical simulations and use them to reconstruct all shear moduli in human skin in vivo.
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