Terahertz pulsed imaging in vivo: measurements and processing methods

Edward P. Parrott; Stanley M. Y. Sy; Thierry Blu; Vincent P. Wallace; Emma Pickwell-MacPherson

doi:10.1117/1.3642002

1 October 2011 Terahertz pulsed imaging in vivo: measurements and processing methods

Edward P. Parrott, Stanley M. Y. Sy, Thierry Blu, Vincent P. Wallace, Emma Pickwell-MacPherson

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Journal of Biomedical Optics, Vol. 16, Issue 10, 106010 (October 2011). https://doi.org/10.1117/1.3642002

Abstract

This paper presents a number of data processing algorithms developed to improve the accuracy of results derived from datasets acquired by a recently designed terahertz handheld probe. These techniques include a baseline subtraction algorithm and a number of algorithms to extract the sample impulse response: double Gaussian inverse filtering, frequency-wavelet domain deconvolution, and sparse deconvolution. In vivo measurements of human skin are used as examples, and a comparison is made of the terahertz impulse response from a number of different skin positions. The algorithms presented enables both the spectroscopic and time domain properties of samples measured in reflection geometry to be better determined compared to previous calculation methods.

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Edward P. Parrott, Stanley M. Y. Sy, Thierry Blu, Vincent P. Wallace, and Emma Pickwell-MacPherson "Terahertz pulsed imaging in vivo: measurements and processing methods," Journal of Biomedical Optics 16(10), 106010 (1 October 2011). https://doi.org/10.1117/1.3642002

Published: 1 October 2011

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