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3 October 2013 Study on reflection of human skin with liquid paraffin as the penetration enhancer by spectroscopy
Kun Chen, Yanmei Liang, Yuan Zhang
Author Affiliations +
Funded by: National Natural Science Foundation of China (NSFC), National Natural Science Foundation of China, Natural Science Foundation of China, Tianjin Foundation of Natural Science
Journal of Biomedical Optics, Vol. 18, Issue 10, 105001 (October 2013). https://doi.org/10.1117/1.JBO.18.10.105001
Abstract
Optical clearing agents can improve tissue optical transmittance by reducing the diffuse reflection. The reflection on in vivo human skin before and after applying anhydrous glycerol and 30 to 50% liquid paraffin glycerol mixed solution are investigated in this paper. From their visible and near-infrared reflection spectroscopy, all of their diffuse reflections are reduced after applying the agents. It is found that the three mixed solutions show stronger effect than that of anhydrous glycerol. These results further prove liquid paraffin can enhance the percutaneous penetration of glycerol and take synergistically optical clearing effect with glycerol over visible and near-infrared wave bands.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Kun Chen, Yanmei Liang, and Yuan Zhang "Study on reflection of human skin with liquid paraffin as the penetration enhancer by spectroscopy," Journal of Biomedical Optics 18(10), 105001 (3 October 2013). https://doi.org/10.1117/1.JBO.18.10.105001
Published: 3 October 2013
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Cited by 7 scholarly publications and 1 patent.
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KEYWORDS
Liquids
Reflection
Diffuse reflectance spectroscopy
Skin
Optical clearing
Spectroscopy
Tissue optics
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