Early diagnosis of traumatic intracranial hematomas

Hasan Ayaz; Meltem Izzetoglu; Kurtulus Izzetoglu; Banu Onaral; Baruch Ben Dor

doi:10.1117/1.JBO.24.5.051411

4 February 2019 Early diagnosis of traumatic intracranial hematomas

Hasan Ayaz, Meltem Izzetoglu, Kurtulus Izzetoglu, Banu Onaral, Baruch Ben Dor

Author Affiliations +

Journal of Biomedical Optics, Vol. 24, Issue 5, 051411 (February 2019). https://doi.org/10.1117/1.JBO.24.5.051411

Abstract

Timing of the intervention for intracranial hematomas is critical for its success, specifically since expansion of the hemorrhage can result in debilitating and sometimes fatal outcomes. Led by Britton Chance, we and an extended team from University of Pennsylvania, Baylor and Drexel universities developed a handheld brain hematoma detector for early triage and diagnosis of head trauma victims. After obtaining de novo Food and Drug Administration clearance, over 200 systems are deployed in all Marine battalion aid stations around the world. Infrascanner, a handheld brain hematoma detection system, is based on the differential near-infrared light absorption of the injured versus the noninjured part of brain. About 12 independent studies have been conducted in the USA, Canada, Spain, Italy, the Netherlands, Germany, Russia, Poland, Afghanistan, India, China, and Turkey. Here, we outline the background and design of the device as well as clinical studies with a total of 1293 patients and 203 hematomas. Infrascanner demonstrates high sensitivity (adults: 92.5% and children: 93%) and specificity (adults: 82.9% and children: 86.5%) in detecting intracranial hematomas >3.5 mL in volume and <2.5 cm from the surface of the brain. Infrascanner is a clinically effective screening solution for head trauma patients in prehospital settings where timely triage is critical.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Hasan Ayaz, Meltem Izzetoglu, Kurtulus Izzetoglu, Banu Onaral, and Baruch Ben Dor "Early diagnosis of traumatic intracranial hematomas," Journal of Biomedical Optics 24(5), 051411 (4 February 2019). https://doi.org/10.1117/1.JBO.24.5.051411

Received: 16 September 2018; Accepted: 3 January 2019; Published: 4 February 2019

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